Raptiva has been approved for use in psoriasis, which, like lupus, is an autoimmune disease. The researchers in this study wanted to see if Raptiva could be effective in treating discoid lupus.
Alternatively, calcineurin inhibitors, pimecrolimus cream or tacrolimus ointment may be used. Imiquimod has also been reported to be helpful in a few patients. If the lesions are becoming unsightly and one really feel something more needs to be done, a drug named Plaquenil will often improve the condition. Patients on Plaquenil need eye exams once a year to prevent damage to the retina of the eye and periodic blood work. Closely related drugs (Aralen, Quinacrine) may be more effective but have more side effects. Other drugs, such as Accutane and Soriatane, can also be used.